Product : VMware, vSphere Replication/v8.1, bundled with vSphere
Feature : Maximum number of protected VMs, General, Architecture
Content Owner:  Viktor van den Berg
Summary
2000 virtual machines
Details
One vSphere Replication appliance and nine additional vSphere Replication servers are required in case of 2000 virtual machines. Per 200 VMs one appliance is required.