Hardware: Because data encryption is performed at the end of the write path, storage efficiency mechanisms are not impaired.
Software: Because HyTrust and Vormetric are end-to-end solutions, encryption is performed at the start of the write path and some efficiency mechanisms (eg. deduplication and compression) are effectively negated.
HPE, SimpliVity [HCI]/4.0.1 U1, 380
Data Encryption Efficiency Impact, Security, Data Services