StorPool storage nodes can be deployed on bare metal only. The storage is presented to the compute nodes through a StorPool native block device driver for Linux-based clients or via iSCSI interface for non-Linux workloads.

StorPool Distributed Storage (StorPool) is accessed through the native StorPool client (initiator, block device driver) for Linux-based hypervisors (KVM).

VMware ESXi, Hyper-V, Xen, XenServer, OracleVM and other OS/hypervisors access storage presented by StorPool through iSCSI.